Cytologic Findings of Epithelial-Myoepithelial Carcinoma of the Salivary Gland: A Case Report.
- Author:
Eun Sook NAM
1
;
Gu KANG
;
Hyung Sik SHIN
Author Information
1. Department of Pathology, Kang Dong Sacred Heart Hospital, Hallym University, Korea.
- Publication Type:Case Report
- Keywords:
Epithelial-myoepithelial carcinoam;
Salivary gland;
Fine needle aspiration cytology
- MeSH:
Acinar Cells;
Biopsy, Fine-Needle;
Cytoplasm;
Eosinophils;
Humans;
Keratins;
Lymph Nodes;
Male;
Middle Aged;
Mitosis;
Neck;
S100 Proteins;
Salivary Glands*;
Submandibular Gland;
Tomography, X-Ray Computed
- From:Korean Journal of Cytopathology
1996;7(1):64-68
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The report of aspiration cytologic findings of epithelial-myoepithelial carcinoma(EMC) in the salivary gland is extremely rare. We present a case of fine needle aspiration cytology(FNAC) from EMC in the right submandibular gland of a 46 years old male patient. Neck CT scan revealed a confined lesion in the submandibular gland without enlargement of the regional lymph node. FNAC from the tumor showed several three-dimensional cellular clusters with admixed normal acinar cells. They frequently formed branching tubular structures composed of two type of cells; darker cells having eosinophilic scanty cytoplasm with round dense nuclei and clear cells having abudant pale cytoplasm with vesicular nuclei at the periphery of clusters. The tumor cells of both types did not show pleomorphism or mitoses. The resected submandibular gland showed an ill-defined whitish firm tumor, measuring 2 X1.5X2cm. The histology revealed an infiltrative tumor showing characteristic two cell types in a duct-like arrangement surrounded by thin basement menbrane. An inner layer of darker cells and outer layer of clear cells were postive for cytokeratin in the former and S-100 protein in the latter on the immunohistochemical stain.
