Imprint Cytology of Hibernoma: A Case Report.
10.3338/kjc.2008.19.2.200
- Author:
Joon Hyuk CHOI
1
;
Duk Seop SHIN
Author Information
1. Department of Pathology, Yeungnam University College of Medicine, Daegu, Korea. joonhyukchoi@ynu.ac.kr
- Publication Type:Case Report
- Keywords:
Hibernoma;
Cytology
- MeSH:
Adipocytes, Brown;
Aged;
Chromatin;
Cytoplasm;
Eosinophils;
Female;
Humans;
Hydrazines;
Lipoma;
S100 Proteins;
Thigh
- From:Korean Journal of Cytopathology
2008;19(2):200-205
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hibernoma is a rare, benign adipose tumor composed of brown fat cells with eosinophilic granular or multivacuolated cytoplasm. The cytologic features of hibernoma have been rarely reported and may mimic other polygonal cell neoplasms. We report the imprint cytologic features of a case of hibernoma in the left thigh of a 68-year-old woman. Microscopic examination showed large, round, or polygonal brown fat cells. The cells were arranged in fragments or clusters. The nuclei were uniformly round with finely granular chromatin. The cytoplasm was multivacuolated or univacuolated. The abundant eosinophilic granular cytoplasm was also present. No nuclear atypia were present. Immunohistochemical staining showed that cells were positive for S-100 protein.
