Cytologic findings of Hodgkin's disease with special emphasis on Reed-Sternberg cells and their variants.
- Author:
Young Hyeh KO
;
Chan Pil PARK
;
Jung Dal LEE
- Publication Type:Original Article
- Keywords:
Hodgkin's disease;
Reed-Sternberg cells;
Lymph node Aspiration cytology
- MeSH:
Hodgkin Disease*;
Lymphocytes;
Reed-Sternberg Cells*;
Sclerosis
- From:Korean Journal of Cytopathology
1991;2(1):1-7
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cytologic findings from five cases with variable types of Hodgkin' disease were reviewed with special emphasis on the Reed-Sternberg (R-S) cells and their variants. Typical R-S and Hodgkin's cells were mono- or binucleated, and nuclei had rounded smooth contour. Acidophilic prominent nucleoli with perinucleolar halo were conspicuous. In comparison to typical Reed-Sternberg cells, L & H (lymphocytic and histiocytic) cells in the lymphocyte predominant type tended to show pop-corn like irregular nuclear contour and to lack the prominent nucleoli. Lacunar cells in the nodular sclerosis type had multilobated nuclei with prominent acidophilic nucleoli. There was no prominent perinucleolar halo in L & H and lacunar cells. In conjuction with the number of Reed-Sternberg cells and back ground findings observed on the smears, the characteristic features of R-S cells and their variants allowed to make typing of Hodgkin's disease.
