Fine Needle Aspiration Cytology of Hepatoblastoma: Report of Two Cases.
- Author:
Young Nyun PARK
1
;
Kwang Gil LEE
;
Chan II PARK
Author Information
1. Department of Pathology, Yonsei University College of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Hepatoblastoma;
Aspiration cytology;
Hepatocellular carcinoma
- MeSH:
Biopsy;
Biopsy, Fine-Needle*;
Carcinoma, Hepatocellular;
Child;
Hematopoiesis, Extramedullary;
Hepatoblastoma*;
Humans;
Liver
- From:Korean Journal of Cytopathology
1990;1(1):98-102
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hepatoblastoma(HB) is a rare embryonic malignant tumor of the liver. Most morphological studies on HB have limited to the histological characteristics and only 3 cases of HB have been described in the cytology literature. We present 2 cases of HB occurring in children aged 1 year and 3 years, respectively. The distinctive cytologic features of fine needle aspiration of HB were clusters of tumor cells showing acinar and trabecular pattern, smaller tumor cells with a high nuclear-cytoplasmic ratio and hyperchromatic nuclei having prominent nucleoli, and the presence of extramedullary hematopoiesis and osteoid material. These features were also found in the cell block and the biopsy specimen, and appeared very useful in the differentiation of HB from hepatocellular carcinoma.