Fine Needle Aspiration Cytology of Extranodal Marginal Zone B cell Lymphoma with Abundant Plasma Cells and Eosinophilic Histiocytes in Parotid Gland.
- Author:
Youngseok LEE
1
;
Jungsuk AN
;
Yang Seok CHAE
;
Bom Woo YEOM
;
Jong Sang CHOI
;
Chul Hwan KIM
Author Information
1. Department of Pathology, Korea University Anam Hospital, Seoul, Korea. chkap@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Extranodal marginal zone B cell lymphoma,Parotid gland;
FNAC
- MeSH:
Arthritis, Rheumatoid;
Biopsy, Fine-Needle*;
Connective Tissue Diseases;
Cytoplasm;
Eosinophils*;
Female;
Histiocytes*;
Humans;
Lupus Erythematosus, Systemic;
Lymphocytes;
Lymphoma, B-Cell, Marginal Zone*;
Middle Aged;
Parotid Gland*;
Plasma Cells*;
Plasma*
- From:Korean Journal of Cytopathology
2007;18(2):165-169
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The authors present the fine needle aspiration cytology (FNAC) cytologic findings of a case of extranodal marginal zone B cell lymphoma (MZBCL), which featured abundant plasma cells and eosinophilic histiocytes arising in both parotid glands. A 49-year-old female presented with palpable masses in both parotid glands. She had been suffering from systemic lupus erythematosus and rheumatoid arthritis. The lesions were evaluated by FNAC and smears showed a small number of clusters of oncocytic cells with abundant eosinophilic granular cytoplasm and small nuclei, intermixed with small to medium-sized lymphoid cells containing round to lobulated nuclei, which suggested Warthin's tumor. Some of lymphoid cells had a plasmacytoid appearance, and some scattered large cells contained a large amount of eosinophilic cytoplasm. Bilateral superficial parotidectomy was performed and a histopathologic study indicated MZBCL with abundant plasma cells, intermixed with eosinophilic histiocytes. The presence of oncocytic cells and a mixture of lymphoid and plasma cells indicates Warthin's tumor, but the cytologic features of a relatively monotonous small to medium-sized lymphoid infiltrate suggest the possibility of MZBCL in the clinical setting of an FNAC study performed on a patient suffering from a connective tissue disease.
