Imprint Cytology of Granular Cell Tumor: A Case Report.
- Author:
Woo Jung SUNG
1
;
Joon Hyuk CHOI
Author Information
1. Department of Pathology Yeungnam University College of Medicine, Daegu, Korea. joonhyukchoi@yumail.ac.kr
- Publication Type:Case Report
- Keywords:
Granular cell tumor;
Soft tissue;
Cytology;
Imprint
- MeSH:
Chromatin;
Cytoplasm;
Eosinophils;
Female;
Granular Cell Tumor*;
Humans;
Lysosomes;
Middle Aged;
Mitosis;
Necrosis;
S100 Proteins
- From:Korean Journal of Cytopathology
2007;18(2):170-174
- CountryRepublic of Korea
- Language:English
-
Abstract:
Granular cell tumor is a rare tumor of the soft tissue and this is characterized by proliferation of large cells with granular appearing eosinophilic cytoplasm. We report the imprint cytologic features of a case of granular cell tumor in the left calf of a 52-year-old woman. Microscopic examination showed moderate cellularity. The tumor cells were arranged both as single cells and in clusters. The cells were large polygonal-shaped and they had small round nuclei with finely granular chromatin and occasionally conspicuous nucleoli. The cytoplasm was abundant eosinophilic and granular. Naked nuclei and spindle-shaped tumor cells were occasionally noted. No mitosis and necrosis were present. The background showed cytoplasmic granular materials. The tumor cells showed positivity for S-100 protein. Ultrastructurally, abundant lysosomes were present in the cytoplasm of the tumor cells.
