A Case of Group O without Anti-A,B due to hypogammaglobuluinemia.
- Author:
Jae Ho LEE
;
Kyung Hae JUNG
;
Kyou Sup HAN
;
Bok Yeun HAN
;
Jong Hyun YOON
;
Sa Ail CHUN
- Publication Type:Case Report
- MeSH:
Agammaglobulinemia;
B-Lymphocytes;
Electrophoresis;
Fathers;
Humans;
Immunoglobulins;
Lymphocyte Subsets;
Mothers;
Saliva;
Young Adult
- From:Korean Journal of Blood Transfusion
1996;7(2):269-273
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
An ABO discrepancy was observed in a 19-year-old man clinically diagnosed as congenital hypogammaglobulinemia. The patient's red cell was typed as group O, and his serum had no ABO isoagglutinins. Absence of A antigen and B antigen on patient's RBC was confirmed by adsorption- elution test and saliva test. A-transferase and B-transferase activities were not demonstrated in patient's serum. Patient's serum protein electrophoresis revealed hypogammaglobulinemia pattern, and immunoglobulin levels were markedly decreased. Complete absence of B lymphocytes was observed on patient's lymphocyte subset profile. Patient's father and mother were typed as blood group O and no abnormalities were recognized in their serum protein electrophoresis patterns and immunoglobulin concentration.
