Some clinical and hematological characteristics of children who had high risk of Acute Lymphoblastic Leukemia (ALL)
- Author:
Vien Van Bui
;
Nam Hoang Nguyen
- Publication Type:Journal Article
- Keywords:
Leukemia;
ALL;
risk factor
- MeSH:
Leukemia;
ALL;
risk factor
- From:Journal of Medical Research
2008;55(3):87-93
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: Acute leukemia is a popular cancer in children, accounting for one third of pediatric malignant diseases. 75% of acute leukemia in children is lymphoblastic leukemia. Objective: To study some clinical and hematological characteristics in juveniles who had high risk with ALL. Subjects and method: The study included 164 patients. This was a prospective, descriptive study. Results: The older children were ones with high risk ALL. The symptoms such as fever, splenomegaly and mediastinal mass in high risk ALL patients were often higher than in the standard risk ALL children. White blood cells and lymphoblasts (80.1 +/- 17.8%) in high risk ALL patients were often higher than in the standard risk ALL children. Reduction of hemoglobin concentration and reticulocyte in high risk ALL patients were lower than in the standard risk ALL children. Conclusion: There were many serious prognostic clinical factors about peripheral blood and bone marrow cells in children with high risk ALL.
