Echocardiographic Assessment of Left Ventricular Diastolic Function in Transitional Circulation Period.
10.4070/kcj.2006.36.9.652
- Author:
Joon Seok HONG
1
;
Jung Yun CHOI
;
Ling ZHU
;
Jung Ha LEE
;
In Sook LIM
;
Yoon Sook CHUNG
;
Chang Won CHOI
;
Kyo Hoon PARK
;
Chang Suk SUH
;
Eun Sook HAN
Author Information
1. Department of Pediatrics, College of Medicine, Seoul National University, Seoul, Korea. choi3628@snubh.org
- Publication Type:Original Article
- Keywords:
Diastolic function
- MeSH:
Echocardiography*;
Echocardiography, Doppler, Color;
Hemodynamics;
Humans;
Infant;
Infant, Newborn;
Mitral Valve;
Parturition;
Relaxation;
Ventricular Function, Left;
Ventricular Septum
- From:Korean Circulation Journal
2006;36(9):652-660
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: During the transitional period from fetal to neonatal life, there are dramatic changes in the newborn circulation. Among these changes, the left ventricular diastolic function can be easily assessed by Doppler measurement of the mitral inflow. However, there are many physiologic and hemodynamic factors responsible for the mitral inflow. This study was designed to evaluate several parameters that represent the left ventricular function during the transitional circulation period. SUBJECTS AND METHODS: Eighteen normal full-term infants were studied by serial two-dimensional, Doppler and color flow echocardiography within 24 hours before and after birth, between 2 days and 6 days after birth and between 7 days and 30 days after birth). RESULTS: One day after birth, the mitral valve (MV) E velocity and E/A increased (37.9+/-7.5 vs. 60.3+/-9.0 and 0.8+/-0.1 vs. 1.1+/-0.1, p<0.01, respectively), but the MV A velocity, the velocity of propagation (Vp), the LV isovolumic relaxation time (IVRT), the corrected IVRT and the tissue Doppler ventricular septum e' and s' did not change. Although Vp/E and a' decreased (1.2+/-0.3 vs. 0.7+/-0.2 and 8.2+/-1.8 vs. 6.5+/-1.7, p<0.05, respectively), the E/e' and the systolic and diastolic pulmonary venous flow velocities increased after birth (6.3+/-1.9 vs. 11.6+/-2.9, and 26.1+/-6.7 vs. 64.5+/-9.6, and 20.9+/-4.1 vs. 63.5+/-17.2, p<0.05, respectively). CONCLUSION: Increased preload plays a key role for the increased MV E/A ratio after birth. Other unknown factors (and possibly including pericardial restriction) may be also responsible for left ventricular diastolic function.
