Association between Quality of Life and Symptom Severity in Obsessive-Compulsive Disorder Patients Using EQ-5D.
- Author:
Sung Nyun KIM
1
;
Woori MOON
;
Jaewook HAN
;
Junhee LEE
Author Information
1. Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Korea. snkim@snu.ac.kr
- Publication Type:Original Article
- Keywords:
Quality of life;
EQ-5D;
Obsessive-compulsive disorder;
Symptom severity
- MeSH:
Ambulatory Care Facilities;
Diagnosis;
Diagnostic and Statistical Manual of Mental Disorders;
Humans;
Mental Disorders;
Obsessive-Compulsive Disorder*;
Quality of Life*;
Seoul
- From:Journal of the Korean Society of Biological Psychiatry
2017;24(3):129-133
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: Obsessive-compulsive disorder (OCD) is a disabling psychiatric disorder, and more attention is recently paid on the quality of life (QoL) in OCD patients. The Euro-QoL-5D (EQ-5D) is a widely used self-report to calculate a single score which represents ‘health utilities’. The aim of this study was to assess the health-related QoL for patients with OCD using the EQ-5D and to examine the relationship between health-related QoL and symptom severity. METHODS: Seventy-three patients with a Diagnostic and Statistical Manual of Mental Disorders (DSM-5) diagnosis of OCD were recruited from the outpatient clinic in Seoul National University Hospital. Symptom severity was assessed using the Yale-Brown Obsessive-Compulsive Scale (YBOCS), and QoL was assessed with the EQ-5D-5L questionnaire. Using Korean valuation study, a single score of QoL was calculated. RESULTS: Most of the OCD patients were relatively young (< 45 years) with the mean YBOCS total score of 19.33. The mean EQ-5D score was 0.71 and significantly correlated with symptom severity (r = -0.483, p < 0.001). 25% of the EQ-5D score was predicted by the YBOCS total score (b = -0.011, p < 0.001) by regression analysis. CONCLUSIONS: OCD patients suffer from lower health-related QoL and QoL significantly decreased as symptom severity increased. The results of the EQ-5D would enable further studies on QoL comparison across medical disease and mental disorders.
