Ketamine as a Rapid-Acting Antidepressant.
- Author:
Daeyoung OH
1
Author Information
1. Department of Neuropsychiatry, Hanyang University College of Medicine, Guri Hospital, Guri, Korea. daeyoh@kaist.ac.kr
- Publication Type:Review
- Keywords:
Depression;
NMDA;
Ketamine;
mTOR
- MeSH:
Antidepressive Agents;
Depression;
Dopamine;
Ketamine;
N-Methylaspartate;
Neurotransmitter Agents;
Norepinephrine;
Serotonin
- From:Journal of the Korean Society of Biological Psychiatry
2013;20(2):29-30
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
First-line therapy of depression is a pharmacological treatment. Many prescribed antidepressants modulate monoamine neurotransmitters including serotonin, norepinephrine and dopamine. Recently, Ketamine, an N-methyl-D-aspartate receptor antagonist, has received attention and has been investigated for clinical trials and neurobiological studies. Here, I introduce ketamine as a rapid-acting antidepressant.
