Association between the Brain-Derived Neurotropic Factor and Attention Deficit Hyperactivity Disorder.
- Author:
Na Ri KANG
1
;
Jae Min SONG
;
Young Sook KWACK
Author Information
1. Department of Psychiatry, Jeju National University Hospital, Jeju, Korea. yskcpy@jejunu.ac.kr
- Publication Type:Review
- Keywords:
Brain-derived neurotropic factor (BDNF);
Attention deficit hyperactivity disorder (ADHD)
- MeSH:
Attention Deficit Disorder with Hyperactivity*;
Brain-Derived Neurotrophic Factor;
Information Services
- From:Journal of the Korean Society of Biological Psychiatry
2018;25(2):21-30
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Attention deficit hyperactivity disorder (ADHD) is a common childhood psychiatric disorder. Recently, it has been suggested that brain-derived neurotropic factor (BDNF) may play a role in the pathogenesis of ADHD. Our aim of this review is to understand the physiological functions of BDNF and its potential relationship with ADHD and therapeutic approaches of ADHD. Searches were conducted in Pubmed and Research Information Service System (RISS). In this review, we summarized important literatures for the physiological functions of BDNF in neurodevelopment, change of serum BDNF level in ADHD, association of BDNF polymorphism and ADHD and potential association of treatment of ADHD with serum BDNF level. Further studies are required to more clearly understand the source and the role of BDNF in ADHD and to develop BDNF based-ADHD treatement.
