Effect of Stress and Serotonin-Transporter-Linked Polymorphic Region Variants on Internet Gaming Disorder in Korean Adults.
- Author:
Hyung Sook HONG
1
;
Jo Eun JEONG
;
Hyun CHO
;
Su Min KWAK
;
Mi Ran CHOI
;
Jung Seok CHOI
;
Sam Wook CHOI
;
Dai Jin KIM
Author Information
1. Department of Psychiatry, College of Medicine, The Catholic University of Korea, Seoul, Korea. kdj922@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Internet gaming disorder;
Stress;
Serotonin-transporter-linked polymorphic region
- MeSH:
Adult*;
Anxiety;
Diagnosis;
Diagnostic and Statistical Manual of Mental Disorders;
Disease Outbreaks;
Humans;
Immunoglobulin D;
Impulsive Behavior;
Internet*;
Logistic Models
- From:Journal of the Korean Society of Biological Psychiatry
2018;25(3):79-87
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: Internet gaming disorder (IGD) is known to be related to stress and the serotonin-transporter-linked polymorphic region (5-HTTLPR) that is known to be associated with stress and has been studied to affect various psychiatric illness outbreaks. We tried to examine the relationship between stress, 5-HTTLPR and IGD. METHODS: A total of 59 participants with IGD, diagnosed according to the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria and 67 normal controls (NC) were enrolled. The IGD group and the NC were compared using chisquare test and independent sample t-test, and logistic regression analysis was used to examine the relationship between stress, the 5-HTTLPR, and IGD. RESULTS: The mean scores for anxiety, impulsivity and stress were significantly higher in the IGD group than in the NC. In addition, there was a significant association between stress and IGD [odds ratio (OR) = 1.172, 95% confidence interval (CI) = 1.008–1.362]. CONCLUSIONS: This study showed that stress would affect IGD. Therefore, the evaluation and management of stress should be included in the diagnosis and treatment of IGD.
