Subclinical Hypothyroidism during Quetiapine Treatment: A Case Report.
- Author:
Kyeong Sae NA
;
Yong Ku KIM
- Publication Type:Case Report
- Keywords:
Bipolar I disorder;
Quetiapine;
Atypical antipsychotics;
Hypothyroidism;
Thyroid gland
- MeSH:
Diagnostic and Statistical Manual of Mental Disorders;
Humans;
Hypothyroidism*;
Thyroid Function Tests;
Thyroid Gland;
Quetiapine Fumarate
- From:Journal of the Korean Society of Biological Psychiatry
2007;14(1):68-71
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Quetiapine is an atypical antipsychotic drug with a benign side effect profile. However, recent studies have reported that thyroid dysfunction is associated with quetiapine treatment. The authors report a patient with DSM-IV bipolar I disorder who developed subclinical hypothyroidism during quetiapine treatment. The patient showed no significant clinical symptoms, but only abnormal thyroid function test findings including antithyroglobulin antibody. The abnormal thyroid function test findings were normalized after discontinuation of quetiapine. The subclinical hypothyroidism developed during quetiapine treatment may be associated with autoimmune process.
