A case of Posterior Cortical Atrophy Presenting with Features of Atypical Dementia.
- Author:
Kee Hyung PARK
1
;
Sung Wan KIM
;
Dong Jin SHIN
;
Hyun Mi PARK
;
Yeong Bae LEE
;
Young Hee SEUNG
Author Information
1. Department of Neurology, Gachon University Gil Medical Center, Incheon, Korea. khpark@gachon.ac.kr
- Publication Type:Original Article
- Keywords:
Posterior cortical atrophy;
Cortical visual dysfunction, Balint's syndrome;
Gerstman syndrome;
Idiomotor apraxia;
Occipitoparietal hypometabolism
- MeSH:
Alzheimer Disease;
Apraxias;
Atrophy;
Brain;
Cholinesterases;
Dementia;
Electrons;
Female;
Gerstmann Syndrome;
Glycogen Storage Disease Type VI;
Humans;
Magnetic Resonance Imaging;
Memory;
Middle Aged;
Neurologic Manifestations;
Passive Cutaneous Anaphylaxis
- From:Journal of the Korean Society of Biological Psychiatry
2008;15(1):46-53
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Posterior cortical atrophy(PCA) is a presenile dementia that presents primarily with signs and symptoms of cortical visual dysfunction, while memory is relatively preserved until the late stage of the disease. We report a patient with PCA, confirmed by brain magnetic resonance imaging (MRI) and F18-fluorodeoxyglucose positron emission tomography(FDG PET). A 58-year-old right-handed woman presented initially with visual dimness and difficulty finding things around her. She had partial Balint's syndrome, partial Gerstmann syndrome, and idiomotor apraxia. She also had a mild memory disturbance, but preserved insight of her disease. Neuropsychological evaluation showed decreased parietal and left temporal functions bilaterally. Brain MRI and F18-FDG PET revealed typical bilateral occipitoparietal atrophy and hypometabolism, which were slightly worse on the right side. Cholinesterase inhibitor administration for 6 months improved the memory impairment slightly, but not the cortical visual dysfunction. This is a typical case of PCA, confirmed by neurologic signs and imaging findings.
