A Case of Convulsive Seizure Development Induced by Clozapine.
- Author:
Man Kil SEO
;
Doh Kwan KIM
;
E Yong KIM
- Publication Type:Original Article
- Keywords:
Clozapine;
Myoclonic jerk;
Convulsive seizure
- MeSH:
Clozapine*;
Electroencephalography;
Humans;
Male;
Myoclonus;
Schizophrenia;
Seizures*
- From:Journal of the Korean Society of Biological Psychiatry
1999;6(1):135-141
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The authors described a case of male schizophrenia who developed myoclonic jerk repeatedly and one episode of convulsive seizure during the treatment of clozapine. According to literatures and reported cases, myoclonic jerks induced in a small amount of clozapine may precede and predict the development of a convulsive seizure. Therefore clinicians have to pay attention to the development of a myoclonic jerk during the administration of clozapine. They may decrease the dosage of clozapine step by step at first in the convulsive state, and observe EEG changes of patients frequently.
