Basic Concept of Gene Microarray.
- Author:
Seung Yong HWANG
- Publication Type:Original Article
- Keywords:
Genome;
DNA chip;
Gene microarray;
Expression;
Bioinformatics
- MeSH:
Base Sequence;
Biotechnology;
Computational Biology;
Drug Discovery;
Gene Expression;
Genome;
Oligonucleotide Array Sequence Analysis
- From:Journal of the Korean Society of Biological Psychiatry
2001;8(2):203-207
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The genome sequencing project has generated and will continue to generate enormous amounts of sequence data including 5 eukaryotic and about 60 prokaryotic genomes. Given this ever-increasing amounts of sequence information new strategies are necessary to efficiently pursue the next phase of the genome project-the elucidation of gene expression patterns and gene product function on a whole genome scale. In order to assign functional information to the genome sequence, DNA chip(or gene microarray) technology was developed to efficiently identify the differential expression pattern of independent biological samples. DNA chip provides a new tool for genome expression analysis that may revolutionize many aspects of biotechnology including new drug discovery and disease diagnostics.
