The Role of Serotonin in pathology and Treatment of the Mood Disorders.
- Author:
In Kwa JUNG
;
Jin Se KIM
- Publication Type:Original Article
- Keywords:
Serotonin;
Mood disorder;
Selective serotonin reuptake inhibitor
- MeSH:
Antidepressive Agents;
Mood Disorders*;
Pathology*;
Pharmacology;
Serotonin*
- From:Journal of the Korean Society of Biological Psychiatry
1997;4(2):168-178
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The serotonin has been known to play important roles in pathology of the mood disorders. We summerize the evidences of serotonin in pathology of the mood disorders in a view of neuroanatomical and neurochemical aspects. Nowaday, the selective serotonin reuptake inhibitors(SSRIs)may be practically the first line of antidepressants with traditional tricyclic antidepressants(TCAs. Authors review the role of serotonin in the treatment of the mood disorders, in a view of the general considerations in selecting antidepressants, pharmacology, therapeutic, indications, side effects, doses of medication, drug-discontinuation syndrome, drug-to-drug interactions, and special therapeutic situations.
