cDNA Microarray in Psychiatry.
- Author:
Byung Hwan YANG
;
Ja Yoon KIM
- Publication Type:Original Article
- Keywords:
cDNA microarray;
Psychiatric genetics;
Pxpharmacogenetics
- MeSH:
Base Sequence;
DNA, Complementary*;
Genetics, Medical;
Mass Screening;
Oligonucleotide Array Sequence Analysis*;
Risk Assessment
- From:Journal of the Korean Society of Biological Psychiatry
2000;7(2):123-130
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The development of inexpensive high throughput methods to identify individual DNA sequences is important to the future growth of medical genetics. This has become increasingly apparent as psychiatric geneticists focus more attention on the molecular basis of complex multifactorial diseases at which most of psychiatric disease is estimated. Furthermore, candidate gene approaches used in identifying disease associated genes necessitate screening large sequence blocks for changes tracking with the disease state. Even after such genes are isolated, large scale mutational analysis will often be needed for risk assessment studies to define the likely medical consequences of carrying a mutated gene. This review provide basic knowledge of up-to-date technology, cDNA microarray which enables above mentioned various research themes.
