The Relation of Family History and beta-Endorphin Levels in Alcohol Dependence.
- Author:
Hee Yeon JEONG
;
In Joon PARK
;
Young Joon KWON
- Publication Type:Original Article
- Keywords:
Alcoholism;
Family history;
beta-Endorphin
- MeSH:
Alcoholics;
Alcoholism*;
beta-Endorphin*;
Blood Glucose;
Ethanol;
Fasting;
Humans;
Hydrocortisone;
Male;
Plasma
- From:Journal of the Korean Society of Biological Psychiatry
1998;5(1):102-106
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: To evaluated the relation of familial history of alcoholism and plasma level of beta-endorphin, ethanol, beta-endorphin, cortisol and blood glucose were compared in 48 male alcoholics and 29 normal controls. METHODS: Subjects are divided into two groups by family history of alcoholism. Blood samples were obtained before and after 0.75mg/kg of ethanol consumption a 7th admission day. RESULTS: 1) The ratio of family history positive to negative of the patient group was 2 to 1. 2) The age at admission of positive family history group was younger than negative groups. 3) There was no significant difference in change of plasma ethanol level among three groups. 4) There was no significant difference in change of plasma beta-endorphin level among three group. 5) There was no significant difference in change of plasma cortisol level among three groups. 6) There was no significant difference in change of fasting blood sugar level between two patients groups.
