The Relation of Onset-Age and beta-Endorphin Levels in Alcohol Dependence.
- Author:
Hee Yeon JEONG
;
In Joon PARK
;
Jin Man KIM
;
Hyuk Hee JIN
- Publication Type:Original Article
- MeSH:
Alcoholics;
Alcoholism*;
beta-Endorphin*;
Blood Glucose;
Ethanol;
Fasting;
Humans;
Hydrocortisone;
Male;
Plasma
- From:Journal of the Korean Society of Biological Psychiatry
1998;5(1):107-113
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: To evaluate the relation of onset-age and plasma level of beta-endorphin, Ethanol, beta-endorphin, cortisol and blood glucose were compared in 48 male alcoholics and 29 normal controls. METHODS: Alcoholics are divided into two groups by onset-age of alcoholism. Blood samples were obtained before and after 0.75gm/kg of ethanol consumption at the 7th admission day. RESULTS: 1) The ratio of onset-age before 25 years to after 25 years of the patients group was 2 to 3. 2) There was no significant difference in age at admission between two patient groups. 3) There was no significant difference in change of plasma ethanol levels among three groups. 4) There was no significant difference in change of plasma beta-endorphin levels among three groups. 5) There was no significant difference in change of plasma cortisol levels among three groups. 6) There was no significant difference in change of fasting blood sugar levels among two patient groups.
