Functional Magnetic Resonance Imaging and Schizophrenia.
- Author:
Kyoo In CHUNG
1
;
Chang Uk LEE
Author Information
1. Department of Psychiatry, College of Medicine The Catholic University of Korea, Seoul, Korea. jihan@catholic.ac.kr
- Publication Type:Review
- Keywords:
fMRI;
Schizophrenia
- MeSH:
Magnetic Resonance Imaging*;
Oxygen;
Pathology;
Schizophrenia*
- From:Journal of the Korean Society of Biological Psychiatry
2004;11(1):3-13
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: Functional magnetic resonance imaging(fMRI) is one of the most useful techniques for assessing localized changes in cerebral blood flow and oxygenation using diverse challenge paradigms. This review presents the results of fMRI studies relating to schizophrenia. METHODS: Several fMRI articles on this subject in psychiatric journals were surveyed. RESULTS: Even with some methodological limitations, most studies showed activity differences between schizophrenics and control subjects. CONCLUSION: fMRI extends our understanding of the pathophysiological basis of schizophrenia and offer an opportunity for the assessment and management of its pathology.