Mean Platelet Component Change according to Stage in Stroke Patients.
- Author:
Jun Hyoung HONG
1
;
Soo Kyung BOK
;
Kyung Ja JO
;
Sang Hyang OH
;
Jong Myung YOON
;
Jongwook LEE
Author Information
1. Department of Rehabilitation Medicine, Konyang College of Medicine, 1Department of Laboratory Medicine, Konyang College of Medicine, Korea. pseudoj@medimail.co.kr
- Publication Type:Original Article
- Keywords:
Platelet activation;
Mean platelet component;
Stroke
- MeSH:
Blood Platelets*;
Humans;
Infarction;
Male;
Mean Platelet Volume;
Platelet Activation;
Platelet Count;
Stroke*
- From:Journal of the Korean Academy of Rehabilitation Medicine
2005;29(1):32-37
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: Decrease of platelet density by degranulation of activated platelet is well correlated with decrease of mean platelet component (MPC) value. We intended to investigate the change of MPC, mean platelet volume, and platelet count according to the stroke stage and difference between ischemic and hemorrhagic infarction. METHOD: Thirty eight patients (ischemic stroke 28 men, hemorrhagic stroke 10 men) and twenty age-matched healthy persons were included in this study. They were divided into acute stage group and subacute stage group. Each of them were sampled by venously and investigated about mean platelet component, mean platelet volume, and platelet counts. RESULTS: In ischemic stroke, there was statically (p <0.05) meaningful decrease of MPC value in acute stage (27.5+/-1.7) compared to control group (28.8+/-0.9). And MPC value in subacute stage showed meaningful increase (28.1+/-1.3) compared to acute stage but still remained in statically lower value compared to control value. In hemorrhagic stroke, there was no meaningful difference of MPC value in acute stage group (28.6+/-2.0) and subacute stage group (27.9+/-1.1) compared to control group. CONCLUSION: In ischemic stroke patients, MPC value in acute stage decreased meaningfully and this change might be useful as a landmark in predicting the activity of infarction.
