Contribution of Nasal Methicillin-resistant Staphylococcus aureus Colonization to Percutaneous Endoscopic Gastrostomy Site Infection and Risk Factors of Wound Infection.
- Author:
Hee Jung OH
1
;
Ki Nam SHIM
;
Hee Jung CHOI
;
Jong Soo LEE
;
Hyun Joo SONG
;
Kum Hei RYU
;
Tae Hun KIM
;
Sung Ae JUNG
;
Kwon YOO
Author Information
1. Department of Internal Medicine, Ewha Medical Research Institute, Ewha Womans University College of Medicine, Seoul, Korea. shimkn@ewha.ac.kr
- Publication Type:Original Article ; English Abstract
- Keywords:
Percutaneous endoscopic gastrostomy;
Peristomal infection;
Colonization;
Methicillin-resistant Staphylococcus aureus
- MeSH:
Aged;
Aged, 80 and over;
Anti-Bacterial Agents/pharmacology;
Diabetes Complications/epidemiology;
Female;
Gastroscopy;
*Gastrostomy;
Humans;
Male;
Methicillin/pharmacology;
*Methicillin Resistance;
Middle Aged;
Nose/microbiology;
Risk Factors;
Staphylococcal Infections/epidemiology/etiology/*microbiology;
Staphylococcus aureus/drug effects/*isolation & purification;
Surgical Wound Infection/epidemiology/etiology/*microbiology
- From:The Korean Journal of Gastroenterology
2007;49(4):225-230
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Peristomal infection is the most common complication of percutaneous endoscopic gastrostomy (PEG) insertion. Methicillin-resistant Staphylococcus aureus (MRSA) is the most commonly implicated organism of peristomal infection. The aims of this study were to determine the contribution of nasal MRSA to wound infection in PEG and the predictors of wound infection. METHODS: A prospective study was conducted on patients undergoing PEG between September 2003 and July 2005. All patients received antibiotics prior to PEG insertion. Nasal swabs were taken from a consecutive series of patients prior to PEG insertion. Wound status of the peristomal site were prospectively evaluated at day 1, 3, and 7 following the insertion of PEG. RESULTS: Thirty-one patients underwent PEG insertion (mean age, 66+/-16 years). Ten patients (32.3%) had MRSA-positive nasal swabs. Peristomal infection did not have any relationship with nasal MRSA colonization (p>0.05). Peristomal infection occurred in 4 (12.9%) cases. The rate of peristomal infections was significantly higher in patients with diabetes mellitus (p<0.05). CONCLUSIONS: Nasal MRSA colonization is not associated with the risk of peristomal infections in patients receiving antibiotics prior to PEG insertion. Diabetes mellitus might be the risk factor for peristomal infection after PEG insertion.
