The Therapeutic Effect of Inhibitory Repetitive Transcranial Magnetic Stimulation on Right Inferior Frontal Gyrus in Subcortical Aphasia.
- Author:
Ji Hun LEE
1
;
Woo Kyoung YOO
;
Kwang Ik JUNG
;
Dong Hyun KIM
;
Dong Sik PARK
;
Hyoung June IM
Author Information
1. Department of Rehabilitation Medicine, Hallym University College of Medicine, Korea. wooky@hallym.ac.kr
- Publication Type:Original Article
- Keywords:
rTMS;
Subcortical aphasia;
Inferior frontal lobe;
Bi-hemispheric language network
- MeSH:
Animals;
Aphasia*;
Aphasia, Broca;
Aphasia, Wernicke;
Humans;
Outcome Assessment (Health Care);
Transcranial Magnetic Stimulation*
- From:Journal of the Korean Academy of Rehabilitation Medicine
2007;31(1):70-77
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To investigate whether suppression of right inferior frontal gyrus (Broca's homologue) by 1 Hz repetitive transcranial magnetic stimulation (rTMS) can improve speech recovery. METHOD: We applied low frequency rTMS on right Broca's homologue twice a week for 6 weeks in eight subcortical aphasia patients who were 3 months to 3 years poststroke onset. They were tested with Korean Version-Western Aphasia Battery before and after procedure. Also, they were tested with Parallel Short Forms for the Korean-BostonNaming Test and Animal Naming Test serially for outcome measure. rTMS was performed with intensity of 80% of motor threshold for 10 min (600 pulses) at 1 Hz frequency. RESULTS: Significant improvement was observed in picture naming at post-rTMS only in nonfluent aphasia patients but not in fluent aphasia patients. CONCLUSION: rTMS may provide a novel treatment for aphasia by possibly modulating the distributed, bi-hemispheric language network.