Short Term Effects of Transdermal Scopolamine Patch for Drooling of Saliva in Patients with Cerebral Palsy.
- Author:
Sung Won ROH
1
;
Chanwoo KIM
;
Taikon KIM
;
Mun Hwan LEE
;
Kyu Hoon LEE
Author Information
1. Department of Rehabilitation Medicine, Hanyang University College of Medicine, Korea. dumitru1@hanyang.ac.kr
- Publication Type:Original Article
- Keywords:
Drooling;
Saliva;
Scopolamine patch
- MeSH:
Cerebral Palsy;
Humans;
Rehabilitation Centers;
Saliva;
Scopolamine Hydrobromide;
Sialorrhea
- From:Journal of the Korean Academy of Rehabilitation Medicine
2010;34(2):185-188
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To investigate the clinical usefulness of the transdermal scopolamine patch applied to control drooling of saliva in patients with cerebral palsy. METHOD: We enrolled twenty two patients with cerebral palsy residing in a rehabilitation center. The mean age of the patients was 24.0 years old. Transdermal scopolamine patch was applied to the patients for 2 weeks. We measured drooling quantity, severity of drooling, and visual analog scale of care givers' labor intensity at pre-application, post 1 week, and post 2 weeks. RESULTS: Drooling quantity decreased significantly from 4.1+/-1.9 ml to 2.8+/-1.5 ml at post 1 week (p<0.01), and 2.2+/-1.6 ml at post 2 weeks (p<0.01). Severity of drooling decreased from 4.1+/-0.8 to 2.9+/-1.1 at post 2 weeks (p<0.01). Visual analog scale of care givers' labor intensity decreased from 78.2+/-17.4 (mm) to 52.7+/-18.6 at post 1 week (p<0.01), and 45.9+/-22.8 at post 2 weeks (p<0.01). CONCLUSION: These findings suggested that the transdermal scopolamine patch is effective to reduce the drooling of saliva in patients with cerebral palsy within short term.
