Cerebral Hemodynamic Evaluation of Diabetes Mellitus by Transcranial Doppler Sonography.
- Author:
Tae Ho KIM
1
;
Doo Sik YOO
;
Soon Yeol CHONG
Author Information
1. Department of Rehabilitation Medicine, College of Medicine, Konkuk University.
- Publication Type:Original Article
- Keywords:
Transcranial doppler sonography;
Diabetes mellitus;
Mean blood flow velocity
- MeSH:
Blood Flow Velocity;
Cholesterol;
Diabetes Mellitus*;
Hemodynamics*;
Humans;
Hyperlipidemias;
Hypertension;
Lipoproteins;
Mass Screening;
Risk Factors;
Smoke;
Smoking;
Ultrasonography, Doppler, Transcranial*
- From:Journal of the Korean Academy of Rehabilitation Medicine
1999;23(4):815-820
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The purpose of this study was to evaluate hemodynamics for diabetes mellitus (DM) by transcranial Doppler sonography (TCD) and to evaluate the influences of risk factors to cerebral hemodynamics in DM. METHOD: We examined 54 normal persons, 17 patients with DM without risk factors, and 15 patients with DM and risk factors. The risk factors were hypertension, smoking, and hyper lipidemia (total cholesterol >240 mg/dl, low density lipoprotein >160 mg/dl). Mean blood flow velocity (MBFV) was also analyzed by Angiodine 2 Doppler system operating at 2 MHz frequency from each subjects. RESULTS: There was a significant decrease of MBFV in the diabetes in comparison to control groups (p<0.05). There was a significant decrease of MBFV in the diabetic risk group as compared to diabetic non-risk group (p<0.05). There was significantly increased total cholesterol, low density lipoprotein, low density lipoprotein/high density lipoprotein ratio in the diabetic risk group as compared to diabetic non-risk group (p<0.05). MBFV significantly decreased with increasing concentration of HbA1C and duration of DM (p<0.05). CONCLUSION: We suggest that transcranial Doppler sonography can be used as one of the useful screening tests for early detection of cerebrovascular diseases in DM.
