Seroactivities to Phenolic Glycolipid I of Mycobacterium leprae Among Leprosy Patients in National sorokdo Hospital and Their Children.
- Author:
Kyu Kwang HWANG
;
Sang Nae CHO
- Publication Type:Original Article
- Keywords:
Fhenolic glycolipid I;
Leprosy;
ELISA
- MeSH:
Antibodies;
Child*;
Enzyme-Linked Immunosorbent Assay;
Humans;
Leprosy*;
Mycobacterium leprae*;
Mycobacterium*;
Phenol*
- From:Korean Journal of Dermatology
1988;26(4):513-517
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Using ELlSA, 83 sera from leprosy patients in National Sorokdo Hospital who are clessified bacteriologically positive and 40 sera from patient's children were tested for a.ntibedy to phenolic glycolipid I of M. leprae. The following results were obtained. I. Non. of 40 contact children was pasitive to PGL- I. 2. Patiente with high bacterial indices were more likely to have antibodies to PGL,- 1. Although the antibody level declined, in general, after multi-drug therapy (MDT), t.here were quite a few with high circulating antibodiees to PGL- I even among the patients bacteriologically below 2.
