Two Cases Report of Subacute Combined Degeneration in Association with Folate Deficiency.
- Author:
Young Jin KO
1
;
Hye Won KIM
;
Jung Soo LEE
;
Soo Jung CHOI
;
Ji Nam SHIN
Author Information
1. Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea.
- Publication Type:Case Report
- Keywords:
Subacute combined degeneration;
Folate deficiency
- MeSH:
Arm;
Brain;
Folic Acid Deficiency;
Folic Acid*;
Humans;
Leg;
Optic Atrophy;
Sensation;
Spinal Cord;
Subacute Combined Degeneration*;
Vitamin B 12 Deficiency
- From:Journal of the Korean Academy of Rehabilitation Medicine
1999;23(2):430-433
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Subacute combined degeneration is the clinical syndrome associated with vitamin B12 deficiency and characterized by usually symmetrical weakness and progressively worsening of, and abnormal sensations of the legs, arms, trunk, or other area, mental abnormalities, and vision difficulties. Subacute combined degeneration primarily affects the spinal cord, but it also includes damage to the brain, the nerves of the eye, and the peripheral (body) nerves. In this study, we report two patients with subacute combined degeneration of the cord in association with folate deficiency. Subacute combined degeneration of the spinal cord and optic atrophy occurred only in the patients with vitamin B12 deficiency. However, diet-induced folic acid deficiency and subacute combined degeneration of the spinal cord which improved significantly after treatment with folic acid has been recorded.
