Effects of Electrical Stimulation on Nerve Regeneration in Peripheral Nerve Injured Rats.
- Author:
Yeung Ki KIM
1
;
Sang Ho AHN
;
Seung Ho JANG
;
Hea Woon PARK
;
Hyun Jin SIN
Author Information
1. Department of Rehabilitation Medicine, Yeungnam University College of Medicine.
- Publication Type:Original Article
- Keywords:
Electrical stimulation;
Nerve regeneration;
Nerve injury
- MeSH:
Animals;
Ankle Joint;
Electric Stimulation*;
Electrodes;
Nerve Regeneration*;
Peripheral Nerves*;
Rats*;
Regeneration;
Sciatic Nerve
- From:Journal of the Korean Academy of Rehabilitation Medicine
1999;23(5):893-898
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To evaluate the efficacy of direct current electrical fields and peripheral external electrical stimulation to promote regeneration of the transected rat sciatic nerve. METHOD: Four groups were studied: three experimental groups and one control group. Cathod distal (CD) group; nerves were treated with 1.0 microampere direct current with the cathode oriented distally to the lesion, anode distal (AD) group; nerves were treated with the anode oriented distally to the lesion, external stimulation (ES) group; nerves were treated with 3 mA, 60 Hz, galvanic current, using a ring electrode at ankle joint 3 times per day. No current was delivered in control group. Electrophysiologic and functional assessments were conducted at 3 weeks postoperatively. RESULTS: All experimental groups showed significantly higher electrophysiologic and functional improvement than the control group. However, there is no significant differece in improvement among experimental groups. CONCLUSION: Both direct current electrical field and peripheral external electrical stimulation can effectively promote peripheral nerve regeneration.
