Relationship between Respiratory Muscle Strength and Cardiac Function in Duchenne Muscular Dystrophy.
- Author:
Seong Woong KANG
1
;
Hyun Joon SHIN
;
Sang Hee IM
;
Sang Chul LEE
;
Won Hyuk CHANG
;
Yong Kyun KIM
;
Jong Chan KIM
Author Information
1. Department of Rehabilitation Medicine and Rehabilitation Institute of Muscular Disease, Yonsei University College of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Duchenne muscular dystrophy;
Respiratory muscle;
Ejection fraction;
Brain natriuretic peptide
- MeSH:
Echocardiography;
Humans;
Muscular Dystrophy, Duchenne;
Natriuretic Peptide, Brain;
Respiratory Muscles;
Stroke Volume
- From:Journal of the Korean Academy of Rehabilitation Medicine
2009;33(3):316-320
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To investigate the relationship between respiratory muscle strength and cardiac function in patients with Duchenne muscular dystrophy (DMD). METHOD: This study included 37 patients with DMD. Cardiac function of patients was evaluated by thoracic echocardiography, which recorded left ventricular ejection fraction (LVEF). Maximal expiratory pressure (MEP) and maximal inspiratory pressure (MIP) representing respiratory muscle strength and blood sampling for brain natriuretic peptide (BNP) were performed. RESULTS: LVEF did not show significant correlation with MIP, MEP or age. However, LVEF was negatively correlated with BNP level. CONCLUSION: Cardiac dysfunction of patients with DMD didn't correlate with age or respiratory muscle strength. Therefore, investigation of cardiac function itself is needed for patients with DMD irrespective of respiratory compromises.
