Bone Metabolism in the Hemiplegic Patients after Stroke.
- Author:
Young Eun KIM
1
;
Tae Du JUNG
;
Ki Hoon LEE
;
Hyun PARK
;
Yang Soo LEE
Author Information
1. Department of Rehabilitation Medicine, College of Medicine, Kyungpook National University.
- Publication Type:Original Article
- Keywords:
25-hydroxyvitamin D (25-OHD);
Parathyroid hormone (PTH);
Hemiplegia;
Stroke;
Bone metabolism
- MeSH:
Calcium;
Hemiplegia;
Humans;
Hyperparathyroidism;
Metabolism*;
Osteocalcin;
Parathyroid Hormone;
Stroke*;
Vitamin D
- From:Journal of the Korean Academy of Rehabilitation Medicine
2001;25(5):842-848
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To assess change of bone metabolism in hemiplegic patients after stroke. METHOD: Sera were collected from 19 hemiplegic patients after stroke. Sera were assayed for 25-hydroxyvitamin D (25-OHD), 1,25-dihydroxyvitamin D (1,25-(OH)2D), parathyroid hormone (PTH), calcium and osteocalcin. RESULTS: Serum 25-OHD and 1,25-(OH)2D concentration were 15.13 mg/mL and 20.88 pg/mL, respectively. Serum PTH was 47.23 pg/mL. In 5 (26%) of the patients, the serum 25-OHD concentration were < 10 ng/mL (deficient level). Ten (52%) of the patients had vitamin D concentrations between 10 and 20 ng/mL (insufficient level). The mean PTH concentration was not significantly higher in patients with deficient levels of 25-OHD (61.80 pg/mL) than those with insufficient (43.63 pg/mL) or sufficient (38.05 pg/mL) levels of 25-OHD. Serum 25-OHD concentration were lower in the late group (11.11 mg/mL) than in the early group (18.05 mg/mL), whereas serum PTH concentration were higher in the late group (58.96 pg/mL) than in the early group (38.70 pg/mL). CONCLUSION: Compensatory hyperparathyroidism with hypovitaminosis D occurred in the hemiplgic patients after stroke, especially more than one year from onset.
