Effect of Radiofrequency Lesioning on Peripheral Nerve Conductivity in Relation to Distance between Lesioning Electrode and Target Tissue in Rats.
- Author:
Hyun Yoon KO
1
;
Yong Beom SHIN
;
Sang Hyo LEE
;
Ha Noon MOOHN
;
Dong Rak KWON
;
Young Hyun AHN
Author Information
1. Department of Rehabilitation Medicine, Pusan National University College of Medicine, Korea. hyko@pusan.ac.kr
- Publication Type:Original Article
- Keywords:
Radiofreqency lesioning;
Effective distance;
Neurophysiologic change;
Peripheral nerve
- MeSH:
Action Potentials;
Animals;
Electrocoagulation;
Electrodes*;
Nerve Tissue;
Peripheral Nerves*;
Rats*;
Rats, Sprague-Dawley;
Sciatic Nerve
- From:Journal of the Korean Academy of Rehabilitation Medicine
2004;28(5):449-453
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To investigate neurophysiologic changes of peripheral nerves, which were injured by radiofrequency thermocoagulation and evaluate an effective distance between the lesioning electrode and target nerve tissue. METHOD: Thirty Sprague-Dawley rats were used and divided into three groups by the distance between the lesioning electrode and the sciatic nerve: 2 mm, 4 mm, 6 mm for each group (10 rats for each group). Radiofrequency lesioning was performed with 1.5 Volt, 1 MHz-frequency and 1 ms duration current for 90 sec. On the first and the fifth day after radiofrequency lesioning, latencies and amplitudes of compound muscle action potential were compared with the baseline values. RESULTS: No statistically significant latency change was observed on the first and the fifth day after lesioning. The amplitude was significantly reduced in group I and II on the first and the fifth day after lesioning, in contrast that, there was no significant change in the group III. CONCLUSION: There was significant decrement in the amplitude after effective radiofrequency lesioning to the sciatic nerve with the distance of 4 mm or less. However, changes of the latencies was not significant. It was suggested that effective distance between raidiofrequency lesioning electrode and target peripheral nerve was 4 mm or less.
