Acute Motor Axonal Neuropathy Associated with Anti-GM1 Antibody: A case report.
- Author:
Hye Won KIM
1
;
Young Jin KO
;
Kyong Hwa KIM
;
Il Su KIM
;
Keun Hyeung RYU
Author Information
1. Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea.
- Publication Type:Case Report
- Keywords:
Acute motor axonal neuropathy (AMAN);
Anti-GM1 antibodies
- MeSH:
Antibodies;
Axons*;
Cauda Equina;
Child;
Diagnosis;
Gadolinium DTPA;
Humans;
Immunoglobulin G;
Magnetic Resonance Imaging;
Male;
Paralysis;
Spine
- From:Journal of the Korean Academy of Rehabilitation Medicine
2000;24(6):1207-1212
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Guillain-Barre syndrme (GBS) has several subtypes that are divided by clinical, electro- physiological, and pathological findings. A novel form of GBS, that is termed acute motor axonal neuropathy (AMAN), is characterized by the selective involvement of motor fibers, and is associated with anti-GM1 antibodies. A 8-year-old male patient were developed ascending, symmetrical paralysis, and areflexia, but no sensory disturbance. Elevated titers of serum IgG anti-GM1 antibodies were detected. His thoracolumbar spine magnetic resonance imaging (MRI) revealed thickening of cauda equina and enhancement of anterior nerve roots of T12-L1 spinal level after Gd-DTPA infusion. Electrophysiological diagnosis was acute motor axonal neuropathy (AMAN). We report this case with review of the literature.
