Serotonin Syndrome in Traumatic Brain Injury Patient: A case report.
- Author:
Yangjoo SONG
1
;
Insun PARK
Author Information
1. Departmetn of Rehabilitation Medicine, Inje University College of Medicine.
- Publication Type:Case Report
- Keywords:
Serotonin syndrome;
Traumatic brain injury;
Sinemet
- MeSH:
Brain Injuries*;
Coma;
Emergency Service, Hospital;
Humans;
Male;
Middle Aged;
Serotonin Syndrome*;
Serotonin*;
Tremor;
Trihexyphenidyl
- From:Journal of the Korean Academy of Rehabilitation Medicine
1998;22(5):1141-1144
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a 47-year old traumatic brain injury male patient who was treated for the rigidity and tremor with sinemet (carbidopa levodopa) and artane (trihexyphenidyl). He came to the emergency room ten days after the stopping of sinemet. Acute onset of increased obtunded, immobile, rigid, deep coma, and minimal response to a deep pain was presented. There was no evidence of the focal neurological signs. Over the next two days, he awoke with a normal mental status. His muscle tone become normal and he returned to home without residual medical problems or complications. We report a serotonin syndrome in a traumatic brain injury patient who was treated with sinemet and artane, which resulted in a dysregulation of serotonin activity.