Diurnal Variation of Plasma Anti-Diuretic Hormone and Relationship to Nocturnal Polyuria after Spinal Cord Injured Patients.
- Author:
In Young SUNG
1
;
Sun Hong SONG
Author Information
1. Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan, College of Medicine.
- Publication Type:Original Article
- Keywords:
Spinal cord injury;
Nocturnal polyuria;
Anti-diuretic hormone(ADH)
- MeSH:
Activities of Daily Living;
Asia;
Classification;
Humans;
Osmolar Concentration;
Plasma*;
Polyuria*;
Radioimmunoassay;
Spinal Cord Injuries;
Spinal Cord*;
Wheelchairs
- From:Journal of the Korean Academy of Rehabilitation Medicine
1998;22(6):1232-1238
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTS: To investigate the effect of anti-diuretic hormone (ADH) on nocturnal polyuria in spinal cord injured patients. METHODS: Eleven quadriplegics, seven paraplegics, and nine normal person participated in this study. Quadriplegics and paraplegics ranged from A to C grades according to the ASIA classification. All participants were independent in activities of daily living on wheelchair level. Their intake and output were measured at every 6 hours for 24 hours. The level of ADH was measured by the radioimmunoassay method. RESULTS: 1) Urine output from midnight to 6:00 A.M. was increased in quadriplegics, but not in paraplegics. 2) ADH at 6:00 A.M. and midnight was decreased in quadriplegics than in controls. No significant change of ADH level was noted in paraplegics. 3) Serum osmolality was higher in quadriplegics than in controls at 6:00 A.M. and midnight. CONCLUSION: This study indicates that the nocturnal polynuria in spinal cord injured patient is partly due to a decreased ADH.
