Influence of Lesion Location on Cortical Recovery Pattern in Hemiparetic Stroke Patients.
- Author:
Sung Ho JANG
1
;
Su Min SON
;
Sang Ho AHN
;
Sang Hyun CHO
;
Han Won JANG
;
Yun Woo CHO
;
Dong Seok YANG
;
Dong Gyu LEE
Author Information
1. Department of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Korea. sumin430@hanmail.net
- Publication Type:Original Article
- Keywords:
Functional magnetic resonance imaging;
Stroke;
Motor recovery;
Hemiplegia
- MeSH:
Brain Stem;
Extremities;
Hand;
Hemiplegia;
Humans;
Internal Capsule;
Magnetic Resonance Imaging;
Oxygen;
Stroke*
- From:Journal of the Korean Academy of Rehabilitation Medicine
2004;28(5):412-417
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The aim of this study was to elucidate how the location of cerebral infarct influences cortical recovery pattern in hemiparetic stroke patients. METHOD: Forty-three chronic stroke patients and 21 control subjects were recruited for the study. The patients were classified into 4 groups according to infarct locations: cortex (CO), corona radiata (CR), posterior limb of the internal capsule (PL), and brainstem (BS). Functional MRI was performed using the blood oxygen level-dependent technique at 1.5 T with the motor task of hand grasp-release movements. RESULTS: The activation pattern of the primary sensori-motor cortex (SM1) was found to be significantly influenced by the lesion locations, but that of the secondary motor area was not (Pearson's chi-square test, p<0.05). The contralateral' SM1 activation was the major response in the control group (85.7%) and in the BS group (75.0%). On the other hand, the major activation pattern was `peri-lesional' in the CO group (peri-lesional 57.1%, peri-lesional and ipsilateral 42.9%), `bilateral activation' in the CR (85.7%) and the PL group (100.0%). CONCLUSION: Our results suggested that motor recovery mechanisms could be different according to location of cerebral infarct.
