Subacute Combined Degeneration of the Spinal Cord in Association with Pernicious Anemia: A case report.
- Author:
Noh Kyoung PARK
1
;
Dong Soo KIM
;
Jong Hyun LEE
;
Jang Hun YOU
;
In Han CHO
Author Information
1. Department of Physical Medicine and Rehabilitation, Sun General Hospital, Korea. kjdmss11@naver.com
- Publication Type:Case Report
- Keywords:
Subacute combined degeneration;
Pernicious anemia
- MeSH:
Anemia, Pernicious*;
Antibodies;
Gait;
Humans;
Intrinsic Factor;
Lower Extremity;
Middle Aged;
Paresthesia;
Proprioception;
Sensation;
Spinal Cord*;
Subacute Combined Degeneration*;
Vibration;
Vitamin B 12 Deficiency
- From:Journal of the Korean Academy of Rehabilitation Medicine
2005;29(6):678-680
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Subacute combined degeneration is a disease of spinal cord involving the posterior and lateral columns due to vitamin B12 deficiency. We experienced a 56-year-old man suffering subacute combined degeneration, characterised by dysesthesia and disturbance of deep sensation such as position sense, proprioception and vibration sense in the lower extremities, and ataxic gait. We reported one patient with subacute combined degeneration of the cord in association with pernicious anemia resulting from inactivation of intrinsic factor by it's antibodies.