A Case of Systemic Vasculitis Presented as Fever of Unknown Origin.
- Author:
Eun Suk JUNG
1
;
Chung Ho KIM
;
Young Youl HYUN
;
Gang Jee KO
;
Byoung Yun HWANG
;
Hee Jin CHEONG
;
Woo Joo KIM
;
Nam Hee WON
Author Information
1. Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea. wjkim@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Fever of unknown origin (FUO);
Systemic vasculitis;
ANCA
- MeSH:
Antibodies, Antineutrophil Cytoplasmic;
Biopsy;
Cyclophosphamide;
Diagnosis;
Ethmoid Sinusitis;
Female;
Fever of Unknown Origin*;
Fever*;
Glomerulonephritis;
Granuloma;
Hematuria;
Humans;
Inflammation;
Malaria;
Middle Aged;
Systemic Vasculitis*;
Vasculitis
- From:
Infection and Chemotherapy
2004;36(6):377-380
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Fever of unknown origin (FUO) means fever that does not resolve spontaneously in the period expected for self-limited infection and whose cause cannot be ascertained despite considerable diagnostic efforts. We experienced a case of FUO associated with systemic vasculitis, which was diagnosed with clinical manifestation, radiographic findings, the presence of anti-neutrophil cytoplasmic antibody (ANCA), and renal biopsy. A 54-year-old female was admitted to our hospital with remittent fever of 3 months. A paranasal sinus (PNS) view revealed maxillary and ethmoidal sinusitis, and urine analysis showed microscopic hematuria. We performed a renal biopsy on the basis of positive ANCA and microscopic hematuria. The renal biopsy showed pauci-immune crescentic glomerulonephritis without granuloma, interstitial inflammation, and small vessel vasculitis. Under the diagnosis of ANCA-associated systemic vasculitis, she was treated with steroid and cyclophosphamide. She showed marked clinical improvement.
