Candida guilliermondii Endophthalmitis in a Patient with Mixed Gastrointestinal Stromal Tumor and Stomach Adenocarcinoma.
- Author:
Kwang Soon AHN
1
;
Jin Woo KHO
;
Jung Hyeun PARK
;
Kyu LEE
;
Sung Nam PARK
;
Hwa Jung LEE
;
Jun Hoon JUNG
;
Min Hee JUNG
Author Information
1. Department of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea. aks1128@hotmail.com
- Publication Type:Case Report
- Keywords:
Candida endophthalmitis;
Candida guilliermondii;
Adenocarcinoma
- MeSH:
Adenocarcinoma*;
Adrenal Cortex Hormones;
Aged;
Anti-Bacterial Agents;
Candida*;
Early Diagnosis;
Emergencies;
Endophthalmitis*;
Gastrointestinal Stromal Tumors*;
Humans;
Immunosuppressive Agents;
Neutropenia;
Risk Factors;
Stomach*
- From:
Infection and Chemotherapy
2005;37(6):359-363
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Candida is the most common etiologic agent causing endogenous endophthalmitis resulting due to hematogenous spread from a remote primary focus. Risk factors for the infection include intravenous drug use, hyperalimentation, surgery, malignancy, diabetes, neutropenia, and the use of broad- spectrum antibiotics and immunosuppressive agents, especially corticosteroids. The outcome of candida endophthalmitis is disappointing. One main problem in the management of this infection is that early diagnosis is difficult. Thus, treatment may be delayed and this which often leads to a poor outcome. Candida endophthalmitis, particularly candida guilliermondii endophthalmitis, is extremely rare, although it is becoming more common as the number of chronically debilitated patients and the use of invasive procedures increase. It is an ophthalmologic emergency and commonly takes a tragic course. Therefore, early suspicion and aggressive management are imperative to prevent visual loss. The authors report a case of candida endophthalmitis caused by Candida guilliermondii in a 65-year-old man with mixed gastrointestinal stromal tumor(GIST) and stomach adenocarcinoma.
