Experimental analgesic and acute anti-inflammatory effects of VK2
- Author:
Que Thi Hoang
;
Huong Giang Nguyen Tran
;
Anh Thi Van Pham
- Publication Type:Journal Article
- Keywords:
VK2;
analgesia;
anti-inflammatory
- MeSH:
VK2;
analgesia;
anti-inflammatory
- From:Journal of Medical Research
2008;55(3):68-73
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: In traditional medicine, liquid extract VK2 has good effects in the treatment of osteoarticular pain. This remedy has its origin from \u201cTam ty thang\u201d of the Eastern traditional medicine. Objective: To evaluate the analgesic and acute anti-inflammatory effects of liquid extract VK2. Subjects and method: The trial was performed on white mice (18-22 g body weight) and albino rats (120 +/- 20 g body weight). These animals were healthy. The prescribed amount of VK2 doses were 27.5 g and 55 g per kg body weight of the mice, 19.25 g and 38.5 g per kg body weight of the rats. Results: The liquid extract of VK2 doses had analgesic effect on acetic acide and themal-induced pain in the mice. The liquid extract of VK2 doses had also acute anti-inflammatory effect through inhibiting carrageenine-induced edema in the hind paw. Conclusion: VK2 had analgesic and anti-inflammatory effects on experimental animals.
