A Case of Disseminated Fusarium Infection Treated by Liposomal Amphotericin B in a Leukemic Patient.
- Author:
Ji Yeon LEE
1
;
Sung Bum KIM
;
Dae Won PARK
;
Sung Hee SHIN
;
Yong Hyun KIM
;
So Young YOON
;
Joong Sik EOM
;
Chul Won CHOI
;
Hee Jin CHEOUNG
;
Woo Joo KIM
;
Jun Suk KIM
;
Jang Su KIM
;
Kap No LEE
Author Information
1. Department of Internal Medicine, Korea University Medical College, Seoul, Korea. wjkim@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Fusariosis;
Liposomal amphotericin B;
Opportunistic infection
- MeSH:
Adult;
Amphotericin B*;
Debridement;
Fusariosis*;
Fusarium*;
Humans;
Immunocompromised Host;
Induction Chemotherapy;
Leukemia, Myeloid, Acute;
Lung;
Opportunistic Infections;
Skin
- From:
Infection and Chemotherapy
2003;35(5):321-324
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Fusarium spp., basically a superficial pathogen, is a newly emerging fungal pathogen of opportunistic infections in immunocompromised patients. At present, although Fusarium spp. are relatively resistant to amphotericin B, the combination of amphotericin B and surgical debridement appear to be optimal treatment for disseminated infection. Recently we experienced a 32-year-old neutropenic patient after induction chemotherapy for acute myelocytic leukemia presented with skin lesions and infiltrations in both lungs. We diagnosed with disseminated fusariosis by skin culture and successfully treated the patient with liposomal amphotericin B. We emphasize a high index of suspicion for skin lesions especially in immunocopromised patients.
