A Case of Cytomegalovirus Enterocolitis and Jejunal Perforation During Immune Reconstitution with Highly Active Antiretroviral Treatment.
- Author:
Se Ho CHOI
1
;
Hyo Sung KANG
;
Sung Ho LEE
;
Jong Hyun LEE
;
Kyung Youn SEON
;
Seung Woo NAM
;
Jae Kwan HWANG
;
Hyoung Shik SHIN
Author Information
1. Department of Internal Medicine, National Medical Center, Seoul, Korea. sdesdk@kornet.net
- Publication Type:Case Report
- Keywords:
Cytomegalovirus;
Enterocolitis;
Immune reconstitution syndrome;
Highly active antiretroviral therapy
- MeSH:
Antiretroviral Therapy, Highly Active;
Asymptomatic Infections;
Cytomegalovirus*;
Enterocolitis*;
Humans;
Immune Reconstitution Inflammatory Syndrome;
Opportunistic Infections
- From:
Infection and Chemotherapy
2006;38(6):398-402
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Immune reconstitution syndrome (IRS) in HIV-infected patients is an adverse consequence of the restoration of pathogen-specific immune responses during the initial months of highly active antiretroviral treatment(HAART). Previously subclinical infections are unmasked or pre-existing opportunistic infections clinically deteriorate as host immunopathological inflammatory responses are switched on. While the eye is the area where Cytomegalovirus(CMV)-associated IRS occurs most often in patients with AIDS, it also can present with intestinal or pulmonary involvement. We present a case report of an HIV-infected patient in whom CMV enterocolitis and jejunal perforation developed after HAART.
