Immunohistochemical Localization of a Dopamine Releasing Protein in Human Brain.
10.11637/kjpa.1994.7.2.171
- Author:
Ki Young SHIN
;
Sang Do BAE
;
Jung Joong KIM
;
Seong Man NAU
;
Myeong Ok KIM
;
Kyung Je CHO
;
Bong Hee LEE
;
Wan sung CHOI
;
Hyun Joon SOHN
;
Sang Ho BAIK
- Publication Type:Original Article
- Keywords:
DARP;
CNS;
Immunohistochemisiry;
Human
- MeSH:
Brain*;
Diencephalon;
Dopamine*;
Glycoproteins;
Humans*;
Inferior Colliculi;
Medulla Oblongata;
Mesencephalon;
Neurons;
Paraventricular Hypothalamic Nucleus;
Strikes, Employee;
Substantia Nigra;
Tyrosine 3-Monooxygenase;
Vestibular Nuclei
- From:Korean Journal of Physical Anthropology
1994;7(2):171-186
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In order to elucidate the existence and locality of DARP in the human brain, immunohistochemical identification was done in the brain tissues. This glycoprotein was distributed in paraventricular nucleus and thalamic reticular nucleus of diencephalon, substantia nigra and inferior colliculus of mesencephalon, medial vestibular nucleus, medial longitudinal nucleus, lateral reticular nucleus of medulla oblongata. And they follows a close distribution to that of catecholamine (CA) rich in either CA fiber or CA neuronal cell groups as previously reported by others using tyrosine hydroxylase (TH) as a marker. This striking similarities in the topographic arrangement of the DARP-positive reaction product and the TH-positive reaction product is another argument favoring the view that DARP is involved in the regulation of catecholaminergic neurons.
