A Case of Disseminated Scedosporium apiospermum Infection in a Liver Transplant Patient.
- Author:
Hyun Gu PARK
1
;
Seong Ho CHOI
;
Ho Suk KANG
;
Ju Hyung SONG
;
Ji Hoon JUNG
;
Min Wook SO
;
Sang Ho CHOI
;
Yang Soo KIM
;
Jun Hee WOO
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. junheewoo@amc.seoul.kr
- Publication Type:Retracted Publication ; Case Report
- Keywords:
Scedosporium apiospermum;
Liver transplantation;
Voriconazole
- MeSH:
Brain Abscess;
Central Nervous System Infections;
Female;
Fungi;
Head;
Humans;
Immunocompromised Host;
Intracranial Hemorrhages;
Liver Transplantation;
Liver*;
Middle Aged;
Mycetoma;
Pneumonia;
Scedosporium*;
Soil;
Sputum
- From:
Infection and Chemotherapy
2006;38(5):290-295
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sedosporium apiospermum is a saprophytic fungus commonly found in soil and polluted water. This organism is known as a cause of mycetoma, which may occur in immunocompetent hosts following trauma. However, in immunocompromised patients, S. apiospermum can also cause life-threatening invasive disease, including central nervous system infection or disseminated infection. We report a fatal case of disseminated S. apiospermum infection in a 46-year-old woman after liver transplantation. Eight days postoperatively, she developed pneumonia, followed by altered mentality in the 15 days. A head CT demonstrated multiple brain abscesses. Sputum and stereotactic-aspirated brain abscess culture yielded S. apiospermum. Despite treatment with voriconazole, the patient died of intracranial hemorrhage.
