A Case of Kikuchi-Fujimoto Disease Presenting as Mesenteric Lymphadenitis.
- Author:
Won Sub CHOI
1
;
Seung Soon LEE
;
Chin Woo KWON
;
Young Seok LEE
;
Sun Young KIM
;
Sun Young CHEON
;
Min Jeong KIM
;
Doo Ryeon CHUNG
Author Information
1. Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang-si, Korea. drchung@hallym.ac.kr
- Publication Type:Case Report
- Keywords:
Kikuchi-Fujimoto disease;
Histiocytic necrotizing lymphadenitis;
Mesenteric lymphadenitis
- MeSH:
Abdomen, Acute;
Abdominal Pain;
Adult;
Anti-Bacterial Agents;
Appendicitis;
Appendix;
Biopsy;
Diagnosis, Differential;
Fever;
Granuloma;
Histiocytes;
Histiocytic Necrotizing Lymphadenitis*;
Humans;
Lymph Nodes;
Lymphatic Diseases;
Mesenteric Lymphadenitis*;
Neck;
Necrosis;
Neutrophils;
Physical Examination;
T-Lymphocytes;
Young Adult
- From:
Infection and Chemotherapy
2006;38(5):304-307
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is a benign, rare, self limitimg disease presenting with mainly cervical lymphadenopathy and fever unresponsive to antibiotics or medical treatment. A 28-year old man presented with fever and right lower quadrant abdominal pain. Physical examination showed abdominal tenderness and rebound tenderness mimicking acute appendicitis. Imaging studies showed normal appendix and other abdominal organs except enlarged multiple mesenteric lymph nodes. Symptoms persisted despite antimicrobial therapy. Multiple tender lymph nodes were palpable on bilateral cervical area at the 7th hospital day. The biopsy of the neck node showed large areas of patchy, irregular necrosis with prominent nuclear debris surrounded by T lymphocytes, histiocytes without neutrophils and granuloma, so he was diagnosed as Kikuchi-Fujimoto disease. With conservative management, clinical improvement was observed. We suggest that Kikuchi-Fujimoto disease with mesenteric lymphadenitis should be added to the differential diagnosis of acute abdomen mimicking acute appendicitis in young adults.
