A Case of Clostridium sordellii Bacteremia in a Patient with Osteosarcoma.
- Author:
Sun You MOON
1
;
Seung Soon LEE
;
Ji Eon WON
;
Youngsu KIM
;
Hyo Jung KIM
;
Han Sung KIM
;
Hee Jung KANG
;
Doo Ryeon CHUNG
Author Information
1. Department of Internal Medicine, Hallym University Sacred Heart Hospital Hallym University College of Medicine, Anyang, Korea. drchung@hallym.ac.kr
- Publication Type:Case Report
- Keywords:
Clostridium sordellii;
Bacteremia;
Osteosarcoma
- MeSH:
Bacillus;
Bacteremia*;
Clostridium sordellii*;
Clostridium*;
Exotoxins;
Humans;
Immunosuppression;
Korea;
Leg;
Mortality;
Osteosarcoma*;
Pathology;
Prognosis;
Skin;
Spores;
Subcutaneous Tissue;
Ulcer
- From:
Infection and Chemotherapy
2006;38(1):51-54
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clostridium sordellii is a gram-positive spore forming anaerobic bacillus, rarely encountered in human infection. It produces several exotoxins which contribute to myonecrosis, pulmonary infection, obstetric infection and bacteremia. C. sordellii bacteremia is very rare and has been reported in few patients with malignancy or immunosuppression. To date, there has been no report in Korea. Mortality is high when deep site infection exists regardless of underlying pathology and immune status. In contrast, superficial skin and subcutaneous tissue infection has a favorable prognosis. We present a case of C. sordellii bacteremia in a patient with osteosarcoma. The patient was admitted for the treatment of the infection at the ulcerative osteosarcoma lesions of the leg, and C. sordellii bacteremia was demonstrated. He was successfully treated with intravenous ampicillin/sulbactam for two weeks.
