A Case of Coincident Multiple Myeloma and Nasal NK/T-Cell Lymphoma.
- Author:
Won Sik LEE
1
Author Information
1. Department of Internal Medicine, Changwon Fatima Hospital, Changwon, Korea. stemcell@korea.com
- Publication Type:Case Report
- Keywords:
Coexistence;
Multiple Myeloma;
Nasal NK/T-cell lymphoma;
Non-Hodgkin's Lymphoma
- MeSH:
Bone Marrow;
Daunorubicin;
Diagnosis;
Drug Therapy;
Electrophoresis;
Female;
Hematemesis;
Humans;
Immunoelectrophoresis;
Immunoglobulin G;
Lymphoma*;
Lymphoma, Non-Hodgkin;
Middle Aged;
Multiple Myeloma*;
Nasopharynx;
Paraproteinemias;
Plasma Cells;
Turbinates;
Vincristine
- From:Korean Journal of Hematology
2004;39(3):182-185
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The coexistence of non-Hodgkin's lymphoma and multiple myeloma is very rare and the coexistence of nasal NK/T-cell lymphoma and multiple myeloma has never been reported in the literature. Recently, a 63-year-old woman was presented with small amount of hematemesis. Bone marrow showed increased immature plasma cell (72.5%). Serum protein electrophoresis showed monoclonal gammopathy (6.5g/dL). Serum immunoelectrophoresis showed IgG and kappa type monoclonality. Microscopic examination of left nasopharynx and inferior turbinate revealed nasal NK/T-cell lymphoma. Six cycles of CHOP (cyclophosphamide, daunomycin, vincristine, prednisone) chemotherapy induced the complete remission of both tumors, but died of cerebral involvement of NK/T-cell lymphoma in 12 months after the diagnosis.