A Case of Idiopathic Hypereosinophilic Syndrome with Deep Vein Thrombosis and Pulmonary Embolism.
- Author:
Jong Mu SUN
1
;
Jong Seok LEE
;
Jae Ho LEE
;
Jin Soo KIM
;
Tae Min KIM
;
Tae Yong KIM
;
Sae Won HAN
;
Yongsang HONG
;
Sung Soo YOON
;
Byoung Kook KIM
;
Seonyang PARK
Author Information
1. Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. Seonpark@plaza.snu.ac.kr
- Publication Type:Case Report
- Keywords:
Hypereosinophilic syndrome;
Thrombosis;
Pulmonary embolism
- MeSH:
Eosinophilia;
Eosinophils;
Hypereosinophilic Syndrome*;
Pulmonary Embolism*;
Thromboembolism;
Thrombosis;
Venous Thrombosis*
- From:Korean Journal of Hematology
2004;39(3):196-199
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of idiopathic hypereosinophilic syndrome (HES) presenting with deep vein thrombosis and subsequent massive pulmonary embolism. The eosinophilia and thromboembolism improved dramatically with systemic corticosteroid and anticoagulation therapy. However, the early and rapid tapering of corticosteroid, in a state of normal eosinophil count and therapeutic PT level, aggravated thromboembolism. An immediate retrial of corticosteroid made disease improve again. The etiology of HES and the pathogenesis of thrombus formation in HES still remain uncertain but corticosteroid in treatment of HES is yet cardinal and should be maintained for a prolonged period of time.
