A Case of Massive Intravascular Hemolysis Associated with Clostiridium perfringens Sepsis.
10.5045/kjh.2007.42.4.409
- Author:
Kyung Sun PARK
1
;
So Young KANG
;
Woo In LEE
Author Information
1. Department of Laboratory Medicine, East-West Neo Medical Center, Kyung Hee University College of Medicine, Seoul, Korea. wileemd@khu.ac.kr
- Publication Type:Case Report
- Keywords:
Clostiridium perfringens;
Massive intravascular hemolysis;
Sepsis
- MeSH:
Adult;
Animals;
Bacteremia;
Cellulitis;
Cholecystitis;
Clostridium perfringens;
Diagnosis;
Foodborne Diseases;
Hemolysis*;
Humans;
Liver Cirrhosis;
Mortality;
Sepsis*;
Soil
- From:Korean Journal of Hematology
2007;42(4):409-413
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clostridium perfringens is an anaerobic, gram-positive rod that inhabits the soil and the intestinal tracts of many animals, including humans. C. perfringens is a major cause of food poisoning, traumatic or nontraumatic myonecrosis, clostridial cellulitis, gangrenous cholecystitis, sepsis or bacteremia, and intravascular hemolysis. Massive intravascular hemolysis is a rare complication of C. perfringens septicemia and has a high mortality rate with an extremely rapid progression. Therefore, aggressive treatment is required as soon as the diagnosis is made. In this study, we report a case of massive intravascular hemolysis due to C. perfringens septicemia in a 34-year-old man with liver cirrhosis.
